Hemolysis-induced acute renal failure in paroxysmal nocturnal hemoglobinuria.
نویسندگان
چکیده
منابع مشابه
A Rare Cause of Reversible Renal Hemosiderosis
Kidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridium difficile infection with possible role of supratherapeutic INR. We discuss the pathophysiology,...
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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening blood disorder characterized by intravascular hemolysis, thrombosis and bone marrow failure. Acute kidney injury, including acute renal failure, have been reported in patients with PNH. We report the case of a 36-year-old male patient with PNH who developed acute kidney injury following an infection of undetermined diagnosis....
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Decreased renal function has been observed in diseases with intravascular haemolysis, including paroxysmal nocturnal haemoglobinuria (PNH). However, the mechanisms via which haemoglobin enhances renal damage in this pathology are not fully known. We report a case of acute renal failure associated to PNH and extensive haemosiderin deposits in tubular cells. Renal biopsy also revealed a strong im...
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and pneumonia. She had a history of unknown cause of recurrent red colored urine for 8 years despite undergoing renal biopsy in a previous hospital (Fig. 1). Initial laboratory findings showed mild anemia and moderate anisocytosis. Urinalysis showed protein (3+) and occult blood (4+). Serum creatinine had increased from 3.5 to 9.1 mg/dL in the four days after admission to our hospital. Serum im...
متن کاملRenal Manifestations in Paroxysmal Nocturnal Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired chronic disorder characterized by a triad of clinical features - hemolytic anemia, pancytopenia, and thrombosis. Not many reports of renal involvement in PNH are available in literature. We present a case series of PNH with renal involvement. We present the data of PNH patients who attended to Departments of General Medicine and Nephrolog...
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ورودعنوان ژورنال:
- Nephron
دوره 66 1 شماره
صفحات -
تاریخ انتشار 1994